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Agency Policy: Any recruiter or agency seeking to work with Infinity Pharmaceuticals (the Company) must initially contact our Human Resources Group and enter into an approved search agreement. A search agreement must be in place prior to submitting a resume for consideration. Regardless of past practice, any resumes submitted by recruiters or search firms to any employee, hiring manager or representative of the Company, in any form without a valid written search agreement in place for that position will be deemed to be the sole property of the Company, and no fee will be paid in the event the candidate is hired.

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Job Locations US-MA-Cambridge
We are a passionate, fun, and innovative team dedicated to advancing novel medicines for people with cancer. We are developing IPI-549, a first-in-class, oral, immuno-oncology product candidate that selectively inhibits PI3K-gamma, in multiple clinical studies. MARIO-275 is a global, randomized, controlled combination study of IPI-549 combined with Opdivo in I/O naïve urothelial cancer patients for which enrollment is expected to be completed in 2020 with data by mid-2021. MARIO-3 is the first IPI-549 combination study in front-line advanced cancer patients and is evaluating IPI-549 in combination with Tecentriq and Abraxane in front-line TNBC and in combination with Tecentriq and Avastin in front-line RCC and is also expected to complete enrollment in 2020 with initial data expected in 2020. In collaboration with Arcus Biosciences, Infinity is evaluating a checkpoint inhibitor-free, novel combination regimen of IPI-549 plus AB928 (dual adenosine receptor antagonist) plus Doxil in advanced TNBC patients. In 2019 Infinity completed enrollment in MARIO-1, a Phase 1/1b study evaluating IPI-549 as a monotherapy and in combination with Opdivo (nivolumab) in patients with advanced solid tumors including patients refractory to checkpoint inhibitor therapy. Data presented from MARIO-1 to date show that IPI-549 has activity and leads to a reduction in the number of circulating myeloid derived suppressor cells (MDSCs) as both a monotherapy and in combination with Opdivo and additional data is expected in 2020. With these studies Infinity is evaluating IPI-549 in the anti-PD-1 refractory, I/O-naïve, and front-line settings.
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